antibacterial activities against e coli atcc 25922  (ATCC)

Journal: RSC Advances

Article Title: A multi-stage computational pipeline and in vitro validation for the discovery of small-molecule translation inhibitors targeting the bacterial ribosome

doi: 10.1039/d6ra01785a

Figure Lengend Snippet: Cartoon representation of E. coli 70S ribosome (PDB ID 4v7v), where small (30S) and large (50S) subunits are displayed with ribosomal proteins on the left. The investigated region, including the peptidyl transferase center on 23S rRNA, is indicated on 50S on the right. The native inhibitor Clindamycin (CLY) is shown in sticks. Mg 2+ ions in the crystal structure are depicted as magenta spheres.

Article Snippet: Among these candidates, only Mitoxantrone and Daunorubicin exhibited antibacterial activity against E. coli ATCC 10536 (Table S4–S6).

Techniques:

Journal: RSC Advances

Article Title: A multi-stage computational pipeline and in vitro validation for the discovery of small-molecule translation inhibitors targeting the bacterial ribosome

doi: 10.1039/d6ra01785a

Figure Lengend Snippet: In vitro inhibition of protein synthesis by Clindamycin (control) and the drug candidates in the E. coli cell-free translation system. Error bars represent standard error of the mean. Any error bars that are not visible are smaller than the data symbols.

Article Snippet: Among these candidates, only Mitoxantrone and Daunorubicin exhibited antibacterial activity against E. coli ATCC 10536 (Table S4–S6).

Techniques: In Vitro, Inhibition, Control

Journal: Food Chemistry: X

Article Title: Improving the functional performance of anthocyanin indicator films through antimicrobial peptides incorporation: Enhanced stability, swelling control, and antibacterial efficacy

doi: 10.1016/j.fochx.2025.103259

Figure Lengend Snippet: A schematic representation of the innovative multifunctional films developed in this study, featuring tryptophan-containing antimicrobial peptides (AMPs) that collectively confer enhanced structural stability, reduced swelling behavior, heightened response sensitivity, and effective antibacterial properties.

Article Snippet: Assessment of the antimicrobial efficacy of AMP–anthocyanin composite films. (A) Antibacterial activity against E. coli (ATCC 25922); (B) Antibacterial activity against S. aureus (ATCC 6538), demonstrating the films' inhibitory potential against both Gram–positive and Gram–negative bacteria.

Techniques:

Journal: Food Chemistry: X

Article Title: Improving the functional performance of anthocyanin indicator films through antimicrobial peptides incorporation: Enhanced stability, swelling control, and antibacterial efficacy

doi: 10.1016/j.fochx.2025.103259

Figure Lengend Snippet: Assessment of the antimicrobial efficacy of AMP–anthocyanin composite films. (A) Antibacterial activity against E. coli (ATCC 25922); (B) Antibacterial activity against S. aureus (ATCC 6538), demonstrating the films' inhibitory potential against both Gram–positive and Gram–negative bacteria. The control film refers to a film prepared under the same conditions as the peptide-containing films, except without the addition of antimicrobial peptides (AMPs). For each experimental condition, three independent biological replicates were performed, and each measurement was repeated in technical triplicate ( n = 3). Statistical significance was indicated as follows: ns (not significant), * p < 0.05, ** p < 0.01, and *** p < 0.001.

Article Snippet: Assessment of the antimicrobial efficacy of AMP–anthocyanin composite films. (A) Antibacterial activity against E. coli (ATCC 25922); (B) Antibacterial activity against S. aureus (ATCC 6538), demonstrating the films' inhibitory potential against both Gram–positive and Gram–negative bacteria.

Techniques: Activity Assay, Bacteria, Control